NEURD: automated proofreading and feature extraction for connectomics.

Celii, B., Papadopoulos, S., Ding, Z., Fahey, P.G., Wang, E., Papadopoulos, C., Kunin, A.B., Patel, S., Bae, J.A., Bodor, A.L., Brittain, D., Buchanan, J., Bumbarger, D.J., Castro, M.A., Cobos, E., Dorkenwald, S., Elabbady, L., Halageri, A., Jia, Z., Jordan, C., Kapner, D., Kemnitz, N., Kinn, S., Lee, K., Li, K., Lu, R., Macrina, T., Mahalingam, G., Mitchell, E., Mondal, S.S., Mu, S., Nehoran, B., Popovych, S., Schneider-Mizell, C.M., Silversmith, W., Takeno, M., Torres, R., Turner, N.L., Wong, W., Wu, J., Yu, S.-C., Yin, W., Xenes, D., Kitchell, L.M., Rivlin, P.K., Rose, V.A., Bishop, C.A., Wester, B., Froudarakis, E., Walker, E.Y., Sinz, F., Seung, H.S., Collman, F., da Costa, N.M., Reid, R.C., Pitkow, X., Tolias, A.S., Reimer, J.,

bioRxiv 2023.03.14.532674

 

Functional connectomics reveals general wiring rule in mouse visual cortex.

Ding, Zhuokun, Fahey, P.G., Papadopoulos, S., Wang, E.Y., Celii, B., Papadopoulos, C., Kunin, A.B., Chang, A., Fu, J., Ding, Zhiwei, Patel, S., Ponder, K., Muhammad, T., Bae, J.A., Bodor, A.L., Brittain, D., Buchanan, J., Bumbarger, D.J., Castro, M.A., Cobos, E., Dorkenwald, S., Elabbady, L., Halageri, A., Jia, Z., Jordan, C., Kapner, D., Kemnitz, N., Kinn, S., Lee, K., Li, K., Lu, R., Macrina, T., Mahalingam, G., Mitchell, E., Mondal, S.S., Mu, S., Nehoran, B., Popovych, S., Schneider-Mizell, C.M., Silversmith, W., Takeno, M., Torres, R., Turner, N.L., Wong, W., Wu, J., Yin, W., Yu, S.-C., Froudarakis, E., Sinz, F., Seung, H.S., Collman, F., da Costa, N.M., Reid, R.C., Walker, E.Y., Pitkow, X., Reimer, J., Tolias, A.S.,

bioRxiv 2023.03.13.531369

Binary and analog variation of synapses between cortical pyramidal neurons.

Dorkenwald, S., Turner, N.L., Macrina, T., Lee, K., Lu, R., Wu, J., Bodor, A.L., Bleckert, A.A., Brittain, D., Kemnitz, N., Silversmith, W.M., Ih, D., Zung, J., Zlateski, A., Tartavull, I., Yu, S.-C., Popovych, S., Wong, W., Castro, M., Jordan, C.S., Wilson, A.M., Froudarakis, E., Buchanan, J., Takeno, M.M., Torres, R., Mahalingam, G., Collman, F., Schneider-Mizell, C.M., Bumbarger, D.J., Li, Y., Becker, L., Suckow, S., Reimer, J., Tolias, A.S., Macarico da Costa, N., Reid, R.C., Seung, H.S.,

Elife 11, e76120, 2022

 

State-dependent pupil dilation rapidly shifts visual feature selectivity.

 Franke, K., Willeke, K.F., Ponder, K., Galdamez, M., Zhou, N., Muhammad, T., Patel, S., Froudarakis, E., Reimer, J., Sinz, F.H., Tolias, A.S.,

Nature 610, 128–134, 2022

 

Sustained deep-tissue voltage recording using a fast indicator evolved for two-photon microscopy.

Liu, Z., Lu, X., Villette, V., Gou, Y., Colbert, K.L., Lai, S., Guan, S., Land, M.A., Lee, J., Assefa, T., Zollinger, D.R., Korympidou, M.M., Vlasits, A.L., Pang, M.M., Su, S., Cai, C., Froudarakis, E., Zhou, N., Patel, S.S., Smith, C.L., Ayon, A., Bizouard, P., Bradley, J., Franke, K., Clandinin, T.R., Giovannucci, A., Tolias, A.S., Reimer, J., Dieudonné, S., St-Pierre, F.,

Cell S0092-8674(22)00916–3, 2022

 

Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity.

Turner, N.L., Macrina, T., Bae, J.A., Yang, R., Wilson, A.M., Schneider-Mizell, C., Lee, K., Lu, R., Wu, J., Bodor, A.L., Bleckert, A.A., Brittain, D., Froudarakis, E., Dorkenwald, S., Collman, F., Kemnitz, N., Ih, D., Silversmith, W.M., Zung, J., Zlateski, A., Tartavull, I., Yu, S.-C., Popovych, S., Mu, S., Wong, W., Jordan, C.S., Castro, M., Buchanan, J., Bumbarger, D.J., Takeno, M., Torres, R., Mahalingam, G., Elabbady, L., Li, Y., Cobos, E., Zhou, P., Suckow, S., Becker, L., Paninski, L., Polleux, F., Reimer, J., Tolias, A.S., Reid, R.C., da Costa, N.M., Seung, H.S.,

Cell 185, 1082-1100.e24.,2022a

Increased Reliability of Visually-Evoked Activity in Area V1 of the MECP2-Duplication Mouse Model of Autism.

 Ash, R.T., Palagina, G., Fernandez-Leon, J.A., Park, J., Seilheimer, R., Lee, S., Sabharwal, J., Reyes, F., Wang, J., Lu, D., Sarfraz, M., Froudarakis, E., Tolias, A.S., Wu, S.M., Smirnakis, S.M.,

J Neurosci 42, 6469–6482., 2022

 

Structure and function of axo-axonic inhibition.

Schneider-Mizell, C.M., Bodor, A.L., Collman, F., Brittain, D., Bleckert, A.A., Dorkenwald, S., Turner, N.L., Macrina, T., Lee, K., Lu, R., Wu, J., Zhuang, J., Nandi, A., Hu, B., Buchanan, J., Takeno, M.M., Torres, R., Mahalingam, G., Bumbarger, D.J., Li, Y., Chartrand, T., Kemnitz, N., Silversmith, W.M., Ih, D., Zung, J., Zlateski, A., Tartavull, I., Popovych, S., Wong, W., Castro, M., Jordan, C.S., Froudarakis, E., Becker, L., Suckow, S., Reimer, J., Tolias, A.S., Anastassiou, C., Seung, H.S., Reid, R.C., Costa, N.M. da,

Elife 10, e73783., 2021


Visuomotor Control in Mice and Primates.

Tehovnik, E.J., Froudarakis, E., Scala, F., Smirnakis, S.M., Patel, S.S., and Tolias, A.T.

Neurosci Biobehav Rev S0149-7634(21)00352-3., 2021

Petascale neural circuit reconstruction: automated methods.

Macrina, T., Lee, K., Lu, R., Turner, N.L., Wu, J., Popovych, S., Silversmith, W., Kemnitz, N., Bae, J.A., Castro, M.A., Dorkenwald, S., Halageri, A., Jia, Z., Jordan, C., Li, K., Mitchell, E., Mondal, S.S., Mu, S., Nehoran, B., Wong, W., Yu, S., Bodor, A.L., Brittain, D., Buchanan, J., Bumbarger, D.J., Cobos, E., Collman, F., Elabbady, L., Fahey, P.G., Froudarakis, E., Kapner, D., Kinn, S., Mahalingam, G., Papadopoulos, S., Patel, S., Schneider-Mizell, C.M., Sinz, F.H., Takeno, M., Torres, R., Yin, W., Pitkow, X., Reimer, J., Tolias, A.S., Reid, R.C., Costa, N.M. da, and Seung, H.S.

bioRxiv 2021.08.04.455162, 2021

 

Rotation-invariant clustering of neuronal responses in primary visual cortex.

Ustyuzhaninov, I., Cadena, S.A., Froudarakis, E., Fahey, P.G., Walker, E.Y., Cobos, E., Reimer, J., Sinz, F.H., Tolias, A.S., Bethge, M., and Ecker, A.S.

Eighth International Conference on Learning Representations 2020

 Object manifold geometry across the mouse cortical visual hierarchy.

Froudarakis, E., Cohen, U., Diamantaki, M., Walker, E.Y., Reimer, J., Berens, P., Sompolinsky, H., and Tolias, A.S.

bioRxiv, 2020.08.20.258798., 2020

EASE: EM-Assiste Source Extraction from calcium imaging data.

Zhou, P., Reimer, J., Zhou, D., Pasarkar, A., Kinsella, I., Froudarakis, E., Yatsenko, D.V., Fahey, P.G., Bodor, A., Buchanan, J.

bioRxiv, 2020.03.25.007468., 2020

 

Inference of synaptic connectivity and external variability in neural microcircuits.

Baker, C., Froudarakis, E., Yatsenko, D., Tolias, A.S., and Rosenbaum, R.

Comput Neurosci 48, 123–147., 2020

The Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions.

Cheng, J.X., Scala, F., Blanco, F.A., Niu, S., Firozi, K., Keehan, L., Mulherkar, S., Froudarakis, E., Li, L., Duman, J.G., Jiang, X., Tolias, K.F.,

J. Neurosci. 2020

 

The Visual Cortex in Context.

Froudarakis, E., Fahey, P.G., Reimer, J., Smirnakis, S.M., Tehovnik, E.J., and Tolias,

Annual Review of Vision Science 5, 2019

 

Target specific functions of EPL interneurons in olfactory circuits.

Liu, G.*, Froudarakis, E.*, Patel, J.M., Kochukov, M.Y., Pekarek, B., Hunt, P.J., Patel, M., Ung, K., Fu, C.-H., Jo, J.

Nature Communications 10, 1–14., 2019

Layer 4 of mouse neocortex differs in cell types and circuit organization between sensory areas.

Scala, F., Kobak, D., Shan, S., Bernaerts, Y., Laturnus, S., Cadwell, C.R., Hartmanis, L., Froudarakis, E., Castro, J.R., Tan, Z.H.

Nature Communications 10, 1–12., 2019

Inception loops discover what excites neurons most using deep predictive models.

Walker, E.Y., Sinz, F.H., Cobos, E., Muhammad, T., Froudarakis, E., Fahey, P.G., Ecker, A.S., Reimer, J., Pitkow, X., and Tolias, A.S.

Nat. Neurosci. 22, 2060–2065., 2019

 

A global map of orientation tuning in mouse visual cortex.

Fahey, P.G., Muhammad, T., Smith, C., Froudarakis, E., Cobos, E., Fu, J., Walker, E.Y., Yatsenko, D., Sinz, F.H., Reimer, J.,

bioRxiv, 745323., 2019

 

 How well do deep neural networks trained on object recognition characterize the mouse visual system? 

Cadena, S.A., Sinz, F.H., Muhammad, T., Froudarakis, E., Cobos, E., Walker, E.Y., Reimer, J., Bethge, M., Tolias, A., and Ecker, A.S.

In NeurIPS Neuro AI Workshop., 2019

 

Stimulus domain transfer in recurrent models for large scale cortical population prediction on video

Sinz, H. F., Ecker, A., Fahey, G. P., Walker, Y. E., Cobos, E., Froudarakis, E., Yatsenko, D., Pitkow, X., Reimer, J., Tolias, A.S.

Neural Information Processing Systems, 2018

A rotation-equivariant convolutional neural network model of primary visual cortex 

Ecker A.S., Sinz F.H., Froudarakis E., Fahey P.G., Cadena S.A., Walker E.Y., Cobos E., Reimer J., Tolias A.S., Bethge M.

ArXiv:1809.10504 (2018)

 

Community-based benchmarking improves spike rate inference from two-photon calcium imaging data.

Berens, P., Freeman, J., Deneux, T., Chenkov, N., McColgan, T., Speiser, A., Macke, J.H., Turaga, S.C., Mineault, P., Rupprecht, P., Gerhard, S., Friedrich, R.W., Friedrich, J., Paninski, L., Pachitariu, M., Harris, K.D., Bolte, B., Machado, T.A., Ringach, D., Stone, J., Rogerson, L.E., Sofroniew, N.J., Reimer, J., Froudarakis, E., Euler, T., Rosón, M.R., Theis, L., Tolias, A.S., Bethge, M.

Computational Biology 14, e1006157, 2018

 

Developmental broadening of inhibitory sensory maps.
Quast, K.B., Ung, K., Froudarakis, E., Huang, L., Herman, I., Addison, A.P., Ortiz-Guzman, J., Cordiner, K., Saggau, P., Tolias, A.S.

Nat. Neurosci. 20, 189–199., 2017

 

Benchmarking Spike Rate Inference in Population Calcium Imaging.

Theis, L., Berens, P., Froudarakis, E., Reimer, J., Román Rosón, M., Baden, T., Euler, T., Tolias, A.S., and Bethge, M.

Neuron 90, 471–482., 2016

 

Response to Comment on “Principles of connectivity among morphologically defined cell types in adult neocortex.

Jiang, X., Shen, S., Sinz, F., Reimer, J., Cadwell, C.R., Berens, P., Ecker, A.S., Patel, S., Denfield, G.H., Froudarakis, E.

Science 353, 1108–1108., 2016

 

Improved Estimation and Interpretation of Correlations in Neural Circuits. Yatsenko, D., Josić, K., Ecker, A.S., Froudarakis, E., Cotton, R.J., and Tolias, A.S.

PLOS Comput. Biol. 11, e1004083., 2016

Pupil Fluctuations Track Fast Switching of Cortical States during Quiet Wakefulness.

Reimer, J., Froudarakis, E., Cadwell, C.R., Yatsenko, D., Denfield, G.H., and Tolias, A.S.

Neuron 84, 355–362., 2014

 

Population code in mouse V1 facilitates readout of natural scenes through increased sparseness.

Froudarakis, E., Berens, P., Ecker, A.S., Cotton, R.J., Sinz, F.H., Yatsenko, D., Saggau, P., Bethge, M., and Tolias, A.S.

Nat. Neurosci. 17, 851–857., 2014


Three-dimensional mapping of microcircuit correlation structure.

Cotton, R.J., Froudarakis, E., Storer, P., Saggau, P., and Tolias, A.S.

Front. Neural Circuits 7., 2013

 

Protection from premature habituation requires functional mushroom bodies in Drosophila.

Acevedo, S.F.*, Froudarakis, E.I.*, Kanellopoulos, A.*, and Skoulakis, E.M.C

Learn. Mem. Cold Spring Harb. N 14, 376–384., 2007

Distinct neuronal circuits mediate experience-dependent, non-associative osmotactic responses in Drosophila.

Acevedo, S.F., Froudarakis, E.I., Tsiorva, A.-A., and Skoulakis, E.M.C.

Mol. Cell. Neurosci. 34, 378–389, 2007

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